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==Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae==
==Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae==
<StructureSection load='3owv' size='340' side='right' caption='[[3owv]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='3owv' size='340' side='right'caption='[[3owv]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3owv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"diplococcus_pneumoniae"_(klein_1884)_weichselbaum_1886 "diplococcus pneumoniae" (klein 1884) weichselbaum 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OWV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OWV FirstGlance]. <br>
<table><tr><td colspan='2'>[[3owv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"diplococcus_pneumoniae"_(klein_1884)_weichselbaum_1886 "diplococcus pneumoniae" (klein 1884) weichselbaum 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OWV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OWV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g8t|1g8t]], [[1zm8|1zm8]], [[3ism|3ism]], [[1oup|1oup]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1g8t|1g8t]], [[1zm8|1zm8]], [[3ism|3ism]], [[1oup|1oup]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">endA, SP_1964 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1313 "Diplococcus pneumoniae" (Klein 1884) Weichselbaum 1886])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">endA, SP_1964 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1313 "Diplococcus pneumoniae" (Klein 1884) Weichselbaum 1886])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3owv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3owv OCA], [http://pdbe.org/3owv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3owv RCSB], [http://www.ebi.ac.uk/pdbsum/3owv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3owv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3owv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3owv OCA], [https://pdbe.org/3owv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3owv RCSB], [https://www.ebi.ac.uk/pdbsum/3owv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3owv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NUCE_STRPN NUCE_STRPN]] By degrading DNA that enters the cell, plays a role in the competence of cells to be transformed.  
[[https://www.uniprot.org/uniprot/NUCE_STRPN NUCE_STRPN]] By degrading DNA that enters the cell, plays a role in the competence of cells to be transformed.  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: London, R E]]
[[Category: London, R E]]
[[Category: Meiss, G]]
[[Category: Meiss, G]]
Retrieved from "https://proteopedia.org/3owv"