3p45: Difference between revisions

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==Crystal structure of apo-caspase-6 at physiological pH==
==Crystal structure of apo-caspase-6 at physiological pH==
<StructureSection load='3p45' size='340' side='right' caption='[[3p45]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
<StructureSection load='3p45' size='340' side='right'caption='[[3p45]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3p45]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P45 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P45 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3p45]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P45 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P45 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CASP6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CASP6 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p45 OCA], [http://pdbe.org/3p45 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3p45 RCSB], [http://www.ebi.ac.uk/pdbsum/3p45 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3p45 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p45 OCA], [https://pdbe.org/3p45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p45 RCSB], [https://www.ebi.ac.uk/pdbsum/3p45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p45 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.  
[[https://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.  


==See Also==
==See Also==
*[[Caspase|Caspase]]
*[[Caspase 3D structures|Caspase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Dominguez, C]]
[[Category: Dominguez, C]]
[[Category: Kiselyov, A]]
[[Category: Kiselyov, A]]
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