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==An immmunodominant CTL epitope from rinderpest virus presented by cattle MHC class I molecule N*01801(BoLA-A11)==
==An immmunodominant CTL epitope from rinderpest virus presented by cattle MHC class I molecule N*01801(BoLA-A11)==
<StructureSection load='3pwu' size='340' side='right' caption='[[3pwu]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3pwu' size='340' side='right'caption='[[3pwu]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3pwu]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PWU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PWU FirstGlance]. <br>
<table><tr><td colspan='2'>[[3pwu]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovin Bovin] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PWU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PWU FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LA-A11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 BOVIN]), B2m ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LA-A11 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 BOVIN]), B2m ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pwu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pwu OCA], [http://pdbe.org/3pwu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pwu RCSB], [http://www.ebi.ac.uk/pdbsum/3pwu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pwu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pwu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pwu OCA], [https://pdbe.org/3pwu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pwu RCSB], [https://www.ebi.ac.uk/pdbsum/3pwu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pwu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q95477_BOVIN Q95477_BOVIN]] Involved in the presentation of foreign antigens to the immune system.[SAAS:SAAS00004076] [[http://www.uniprot.org/uniprot/HEMA_RINDR HEMA_RINDR]] Attaches the virus to cell receptors and thereby initiating infection. Binding of H protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity). Down-regulates human MCP/CD46 cell surface expression.<ref>PMID:9811778</ref>  [[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.  
[[https://www.uniprot.org/uniprot/Q95477_BOVIN Q95477_BOVIN]] Involved in the presentation of foreign antigens to the immune system.[SAAS:SAAS00004076] [[https://www.uniprot.org/uniprot/HEMA_RINDR HEMA_RINDR]] Attaches the virus to cell receptors and thereby initiating infection. Binding of H protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity). Down-regulates human MCP/CD46 cell surface expression.<ref>PMID:9811778</ref>  [[https://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Beta-2 microglobulin|Beta-2 microglobulin]]
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bovin]]
[[Category: Bovin]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Lk3 transgenic mice]]
[[Category: Gao, F]]
[[Category: Gao, F]]
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