1ug7: Difference between revisions
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<StructureSection load='1ug7' size='340' side='right'caption='[[1ug7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='1ug7' size='340' side='right'caption='[[1ug7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ug7]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1ug7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UG7 FirstGlance]. <br> | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 2610208M17 ([ | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 2610208M17 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ug7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ug7 OCA], [https://pdbe.org/1ug7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ug7 RCSB], [https://www.ebi.ac.uk/pdbsum/1ug7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ug7 ProSAT], [https://www.topsan.org/Proteins/RSGI/1ug7 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/AIDA_MOUSE AIDA_MOUSE]] Acts as a ventralizing factor during embryogenesis (By similarity). Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 05:32, 15 June 2022
Solution structure of four helical up-and-down bundle domain of the hypothetical protein 2610208M17Rik similar to the protein FLJ12806
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Large Structures
- Lk3 transgenic mice
- Aoki, M
- Arakawa, T
- Carninci, P
- Hayashizaki, Y
- Hirota, H
- Inoue, M
- Kawai, J
- Kigawa, T
- Koshiba, S
- Li, H
- Matsuda, T
- Osanai, T
- Structural genomic
- Seki, E
- Shirouzu, M
- Tanaka, A
- Terada, M
- Tomizawa, T
- Yabuki, T
- Yokoyama, S
- Yoshida, M
- Four helical up-and-down bundle
- Hypothetical protein flj12806
- Rsgi
- Unknown function