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==Crystal structure of the M. tuberculosis beta clamp==
==Crystal structure of the M. tuberculosis beta clamp==
<StructureSection load='3rb9' size='340' side='right' caption='[[3rb9]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='3rb9' size='340' side='right'caption='[[3rb9]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3rb9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RB9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RB9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3rb9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RB9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RB9 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dnaN, MT0002, MTCY10H4.0, MTV029.02, Rv0002 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dnaN, MT0002, MTCY10H4.0, MTV029.02, Rv0002 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rb9 OCA], [http://pdbe.org/3rb9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3rb9 RCSB], [http://www.ebi.ac.uk/pdbsum/3rb9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3rb9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rb9 OCA], [https://pdbe.org/3rb9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rb9 RCSB], [https://www.ebi.ac.uk/pdbsum/3rb9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rb9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DPO3B_MYCTU DPO3B_MYCTU]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA (By similarity).  
[[https://www.uniprot.org/uniprot/DPO3B_MYCTU DPO3B_MYCTU]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA (By similarity).  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 3rb9" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3rb9" style="background-color:#fffaf0;"></div>
==See Also==
*[[DNA polymerase|DNA polymerase]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Large Structures]]
[[Category: Myctu]]
[[Category: Myctu]]
[[Category: Kukshal, V]]
[[Category: Kukshal, V]]
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