3rbl: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
Line 1: Line 1:


==Crystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the apo form==
==Crystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the apo form==
<StructureSection load='3rbl' size='340' side='right' caption='[[3rbl]], [[Resolution|resolution]] 3.24&Aring;' scene=''>
<StructureSection load='3rbl' size='340' side='right'caption='[[3rbl]], [[Resolution|resolution]] 3.24&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3rbl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RBL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RBL FirstGlance]. <br>
<table><tr><td colspan='2'>[[3rbl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RBL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RBL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rbf|3rbf]], [[3rch|3rch]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3rbf|3rbf]], [[3rch|3rch]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AADC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AADC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aromatic-L-amino-acid_decarboxylase Aromatic-L-amino-acid decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.28 4.1.1.28] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aromatic-L-amino-acid_decarboxylase Aromatic-L-amino-acid decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.28 4.1.1.28] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rbl OCA], [http://pdbe.org/3rbl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3rbl RCSB], [http://www.ebi.ac.uk/pdbsum/3rbl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3rbl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rbl OCA], [https://pdbe.org/3rbl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rbl RCSB], [https://www.ebi.ac.uk/pdbsum/3rbl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rbl ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/DDC_HUMAN DDC_HUMAN]] Aromatic L-amino acid decarboxylase deficiency. The disease is caused by mutations affecting the gene represented in this entry.  
[[https://www.uniprot.org/uniprot/DDC_HUMAN DDC_HUMAN]] Aromatic L-amino acid decarboxylase deficiency. The disease is caused by mutations affecting the gene represented in this entry.  
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DDC_HUMAN DDC_HUMAN]] Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.  
[[https://www.uniprot.org/uniprot/DDC_HUMAN DDC_HUMAN]] Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 26: Line 26:
==See Also==
==See Also==
*[[DOPA decarboxylase|DOPA decarboxylase]]
*[[DOPA decarboxylase|DOPA decarboxylase]]
*[[User:Brian Hernandez/DOPA Decarboxylase|User:Brian Hernandez/DOPA Decarboxylase]]
== References ==
== References ==
<references/>
<references/>
Line 33: Line 32:
[[Category: Aromatic-L-amino-acid decarboxylase]]
[[Category: Aromatic-L-amino-acid decarboxylase]]
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Cellini, B]]
[[Category: Cellini, B]]
[[Category: Cutruzzola, F]]
[[Category: Cutruzzola, F]]
Retrieved from "https://proteopedia.org/3rbl"