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==Crystal structure of the MukE-MukF complex==
==Crystal structure of the MukE-MukF complex==
<StructureSection load='3rpu' size='340' side='right' caption='[[3rpu]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
<StructureSection load='3rpu' size='340' side='right'caption='[[3rpu]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3rpu]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RPU FirstGlance]. <br>
<table><tr><td colspan='2'>[[3rpu]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RPU FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3euh|3euh]], [[3euj|3euj]], [[3euk|3euk]], [[1t98|1t98]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3euh|3euh]], [[3euj|3euj]], [[3euk|3euk]], [[1t98|1t98]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b0922, JW0905, kicB, mukF, mukF (kicB) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), b0923, JW0906, kicA, mukE, MukE (kicA, ycbA, ycbA) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b0922, JW0905, kicB, mukF, mukF (kicB) ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), b0923, JW0906, kicA, mukE, MukE (kicA, ycbA, ycbA) ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rpu OCA], [http://pdbe.org/3rpu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3rpu RCSB], [http://www.ebi.ac.uk/pdbsum/3rpu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3rpu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rpu OCA], [https://pdbe.org/3rpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rpu RCSB], [https://www.ebi.ac.uk/pdbsum/3rpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rpu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MUKF_ECOLI MUKF_ECOLI]] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.<ref>PMID:8602138</ref>  [[http://www.uniprot.org/uniprot/MUKE_ECOLI MUKE_ECOLI]] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.<ref>PMID:8602138</ref>   
[[https://www.uniprot.org/uniprot/MUKF_ECOLI MUKF_ECOLI]] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.<ref>PMID:8602138</ref>  [[https://www.uniprot.org/uniprot/MUKE_ECOLI MUKE_ECOLI]] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.<ref>PMID:8602138</ref>   
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 3rpu" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3rpu" style="background-color:#fffaf0;"></div>
==See Also==
*[[Condensin|Condensin]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Ecoli]]
[[Category: Large Structures]]
[[Category: Ghirlando, R]]
[[Category: Ghirlando, R]]
[[Category: Gloyd, M]]
[[Category: Gloyd, M]]
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