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==Crystal structure of apo form of acetate kinase (AckA) from Salmonella typhimurium==
==Crystal structure of apo form of acetate kinase (AckA) from Salmonella typhimurium==
<StructureSection load='3slc' size='340' side='right' caption='[[3slc]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='3slc' size='340' side='right'caption='[[3slc]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3slc]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SLC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SLC FirstGlance]. <br>
<table><tr><td colspan='2'>[[3slc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SLC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SLC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sk3|3sk3]], [[1g99|1g99]], [[2iir|2iir]], [[3p4i|3p4i]], [[2e1y|2e1y]], [[1saz|1saz]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3sk3|3sk3]], [[1g99|1g99]], [[2iir|2iir]], [[3p4i|3p4i]], [[2e1y|2e1y]], [[1saz|1saz]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ackA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ackA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetate_kinase Acetate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.1 2.7.2.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Acetate_kinase Acetate kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.1 2.7.2.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3slc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3slc OCA], [http://pdbe.org/3slc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3slc RCSB], [http://www.ebi.ac.uk/pdbsum/3slc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3slc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3slc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3slc OCA], [https://pdbe.org/3slc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3slc RCSB], [https://www.ebi.ac.uk/pdbsum/3slc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3slc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ACKA_SALTY ACKA_SALTY]] Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Has broad substrate specificity and can also utilize GTP, UTP and CTP. Can also phosphorylate propionate, but has very low activity with formate and is inactive with butyrate.[HAMAP-Rule:MF_00020]<ref>PMID:23031654</ref>   
[[https://www.uniprot.org/uniprot/ACKA_SALTY ACKA_SALTY]] Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Has broad substrate specificity and can also utilize GTP, UTP and CTP. Can also phosphorylate propionate, but has very low activity with formate and is inactive with butyrate.[HAMAP-Rule:MF_00020]<ref>PMID:23031654</ref>   
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Bacillus typhimurium loeffler 1892]]
[[Category: Bacillus typhimurium loeffler 1892]]
[[Category: Acetate kinase]]
[[Category: Acetate kinase]]
[[Category: Large Structures]]
[[Category: Chittori, S]]
[[Category: Chittori, S]]
[[Category: Murthy, M R.N]]
[[Category: Murthy, M R.N]]
Retrieved from "https://proteopedia.org/3slc"