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==Crystal structure of the MAPK binding domain of MKP7==
==Crystal structure of the MAPK binding domain of MKP7==
<StructureSection load='3tg3' size='340' side='right' caption='[[3tg3]], [[Resolution|resolution]] 2.67&Aring;' scene=''>
<StructureSection load='3tg3' size='340' side='right'caption='[[3tg3]], [[Resolution|resolution]] 2.67&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3tg3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TG3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TG3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3tg3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TG3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TG3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tg1|3tg1]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3tg1|3tg1]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DUSP16, KIAA1700, MKP7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DUSP16, KIAA1700, MKP7 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tg3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tg3 OCA], [http://pdbe.org/3tg3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3tg3 RCSB], [http://www.ebi.ac.uk/pdbsum/3tg3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3tg3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tg3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tg3 OCA], [https://pdbe.org/3tg3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tg3 RCSB], [https://www.ebi.ac.uk/pdbsum/3tg3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tg3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DUS16_HUMAN DUS16_HUMAN]] Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.<ref>PMID:11489891</ref> <ref>PMID:15888437</ref>   
[[https://www.uniprot.org/uniprot/DUS16_HUMAN DUS16_HUMAN]] Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.<ref>PMID:11489891</ref> <ref>PMID:15888437</ref>   
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 3tg3" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3tg3" style="background-color:#fffaf0;"></div>
==See Also==
*[[MAP kinase phosphatase|MAP kinase phosphatase]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Liu, X]]
[[Category: Liu, X]]
[[Category: Wang, Z X]]
[[Category: Wang, Z X]]
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