6zc4: Difference between revisions
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==Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling== | ==Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling== | ||
<StructureSection load='6zc4' size='340' side='right'caption='[[6zc4]]' scene=''> | <StructureSection load='6zc4' size='340' side='right'caption='[[6zc4]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZC4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZC4 FirstGlance]. <br> | <table><tr><td colspan='2'>[[6zc4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZC4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZC4 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zc4 OCA], [https://pdbe.org/6zc4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zc4 RCSB], [https://www.ebi.ac.uk/pdbsum/6zc4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zc4 ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=QEZ:5-bromanyl-2-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonylamino)benzoic+acid'>QEZ</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DKFZp586M1622, DVL3, hCG_40299 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zc4 OCA], [https://pdbe.org/6zc4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zc4 RCSB], [https://www.ebi.ac.uk/pdbsum/6zc4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zc4 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Heinemann U]] | [[Category: Heinemann, U]] | ||
[[Category: Oschkinat H]] | [[Category: Oschkinat, H]] | ||
[[Category: Roske Y]] | [[Category: Roske, Y]] | ||
[[Category: Dvl]] | |||
[[Category: Inhibitor]] | |||
[[Category: Pdz]] | |||
[[Category: Peptide binding protein]] | |||
[[Category: Signalling]] | |||
[[Category: Wnt]] | |||
Revision as of 07:02, 20 July 2022
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling
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