Stringent starvation protein: Difference between revisions

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'''Stringent starvation protein''' A (SspA) is an RNA polymerase-associated protein involved in nucleotide metabolism acid tolerance and virulence of bacteria<ref>PMID:32785630</ref>.
'''Stringent starvation protein''' A (SspA) is an RNA polymerase-associated protein involved in nucleotide metabolism acid tolerance and virulence of bacteria<ref>PMID:32785630</ref>.
 
In ''Francisella'' virulence, a set of regulators are essensial for its activation.  These regulators include the heterdimer of SspA, macrophage growth locus A (MglA) and pathogenicity island gene regulator (PigR).  The guanosine-tetraphosphate (ppGpp) is also involved in coordinating the virulence.
== Disease ==
== Disease =s


== Relevance ==
== Relevance ==

Revision as of 08:04, 24 July 2022

SspA (pink, yellow) complex with MglA (green, grey), ppGpp, glycerol, PEG400 (PDB ID 5u51)

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References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky