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==Crystal structure of aW116R mutant of nitrile hydratase from Pseudonocardia thermophilla==
==Crystal structure of aW116R mutant of nitrile hydratase from Pseudonocardia thermophilla==
<StructureSection load='3vyh' size='340' side='right' caption='[[3vyh]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
<StructureSection load='3vyh' size='340' side='right'caption='[[3vyh]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3vyh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_19285 Atcc 19285]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VYH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VYH FirstGlance]. <br>
<table><tr><td colspan='2'>[[3vyh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_19285 Atcc 19285]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VYH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vyg|3vyg]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3vyg|3vyg]]</div></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrile_hydratase Nitrile hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.84 4.2.1.84] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Nitrile_hydratase Nitrile hydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.84 4.2.1.84] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vyh OCA], [http://pdbe.org/3vyh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vyh RCSB], [http://www.ebi.ac.uk/pdbsum/3vyh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vyh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vyh OCA], [https://pdbe.org/3vyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vyh RCSB], [https://www.ebi.ac.uk/pdbsum/3vyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vyh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NHAA_PSETH NHAA_PSETH]] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. [[http://www.uniprot.org/uniprot/NHAB_PSETH NHAB_PSETH]] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides.  
[[https://www.uniprot.org/uniprot/NHAA_PSETH NHAA_PSETH]] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. [[https://www.uniprot.org/uniprot/NHAB_PSETH NHAB_PSETH]] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides.  


==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Atcc 19285]]
[[Category: Atcc 19285]]
[[Category: Large Structures]]
[[Category: Nitrile hydratase]]
[[Category: Nitrile hydratase]]
[[Category: Arakawa, T]]
[[Category: Arakawa, T]]

Revision as of 19:10, 27 July 2022

Crystal structure of aW116R mutant of nitrile hydratase from Pseudonocardia thermophilla

3vyh, resolution 1.63Å

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