Stereochemistry: Difference between revisions
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== Chirality == | == Chirality == | ||
Chiral molecules are like your hands. There are two versions, left and right, and they are mirror images (or enantiomers). The initial scenes shows how four different substituents on a tetrahedral center leads to two possible configurations. It is impossible to superimpose the two molecules without breaking some of the bonds (i.e. swapping two of the substituents. | Chiral molecules are like your hands. There are two versions, left and right, and they are mirror images (or enantiomers). The initial scenes shows how four different substituents on a tetrahedral center leads to two possible configurations. It is impossible to superimpose the two molecules without breaking some of the bonds (i.e. swapping two of the substituents). | ||
If you make a fist with your right hand and hold out your left hand flat, they are still considered mirror images because a hand is still a hand, even when you make a fist. Similarly, you sometimes have to rotate around some single bonds to have a pair of more complex enantiomers actually look like mirror images. | If you make a fist with your right hand and hold out your left hand flat, they are still considered mirror images because a hand is still a hand, even when you make a fist. Similarly, you sometimes have to rotate around some single bonds to have a pair of more complex enantiomers actually look like mirror images. | ||
<table><tr><td><applet load='' name='A' size='300' frame='true' scene='82/824489/Rconfig/4'/></td><td><applet load='' name='B' size='300' frame='true' scene='82/824489/Sconfig/4'/></td></tr></table> | <table><tr><td><applet load='' name='A' size='300' frame='true' scene='82/824489/Rconfig/4'/></td><td><applet load='' name='B' size='300' frame='true' scene='82/824489/Sconfig/4'/></td></tr></table> | ||
== Explore it yourself == | |||
You can rotate the left and the right molecule by dragging them. Try rotating the right molecule so that is looks exactly the same as the left molecule. Or imagine a mirror between the two molecules, and rotate them that the same atoms are on top and on the bottom, but left and right is reversed. | |||
<jmol> | <jmol> | ||