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==Crystal structure of the eukaryotic initiation factor==
==Crystal structure of the eukaryotic initiation factor==
<StructureSection load='3wj9' size='340' side='right' caption='[[3wj9]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
<StructureSection load='3wj9' size='340' side='right'caption='[[3wj9]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3wj9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fission_yeast Fission yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WJ9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3wj9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Fission_yeast Fission yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WJ9 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPBC4B4.04 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPBC4B4.04 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wj9 OCA], [http://pdbe.org/3wj9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wj9 RCSB], [http://www.ebi.ac.uk/pdbsum/3wj9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wj9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wj9 OCA], [https://pdbe.org/3wj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wj9 RCSB], [https://www.ebi.ac.uk/pdbsum/3wj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wj9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/EIF2A_SCHPO EIF2A_SCHPO]] Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins (By similarity).  
[[https://www.uniprot.org/uniprot/EIF2A_SCHPO EIF2A_SCHPO]] Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins (By similarity).  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 3wj9" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3wj9" style="background-color:#fffaf0;"></div>
==See Also==
*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Fission yeast]]
[[Category: Fission yeast]]
[[Category: Large Structures]]
[[Category: Ito, T]]
[[Category: Ito, T]]
[[Category: Kashiwagi, K]]
[[Category: Kashiwagi, K]]
Retrieved from "https://proteopedia.org/3wj9"