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==Crystal Structure of Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) bound to an allosteric inhibitor and AMP-PNP==
==Crystal Structure of Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) bound to an allosteric inhibitor and AMP-PNP==
<StructureSection load='7qpn' size='340' side='right'caption='[[7qpn]]' scene=''>
<StructureSection load='7qpn' size='340' side='right'caption='[[7qpn]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QPN FirstGlance]. <br>
<table><tr><td colspan='2'>[[7qpn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QPN FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qpn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qpn OCA], [https://pdbe.org/7qpn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qpn RCSB], [https://www.ebi.ac.uk/pdbsum/7qpn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qpn ProSAT]</span></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=DVF:5-methyl-2-(2-propan-2-ylphenyl)-~{N}-(pyridin-2-ylmethyl)pyrrolo[3,2-d]pyrimidin-4-amine'>DVF</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7qie|7qie]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qpn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qpn OCA], [https://pdbe.org/7qpn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qpn RCSB], [https://www.ebi.ac.uk/pdbsum/7qpn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qpn ProSAT]</span></td></tr>
</table>
</table>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Howard TD]]
[[Category: Howard, T D]]
[[Category: Ogg DT]]
[[Category: Ogg, D T]]
[[Category: Allosteric binding]]
[[Category: Lipid kinase]]
[[Category: Non-atp-competitive inhibitor]]
[[Category: Phosphatidylinositol 5-phosphate]]
[[Category: Transferase]]

Revision as of 05:09, 10 August 2022

Crystal Structure of Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) bound to an allosteric inhibitor and AMP-PNP

7qpn, resolution 1.95Å

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