3zcm: Difference between revisions

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==Small molecule inhibitors of the LEDGF site of HIV integrase identified by fragment screening and structure based design.==
==Small molecule inhibitors of the LEDGF site of HIV integrase identified by fragment screening and structure based design.==
<StructureSection load='3zcm' size='340' side='right' caption='[[3zcm]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3zcm' size='340' side='right'caption='[[3zcm]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3zcm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aids_virus Aids virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZCM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZCM FirstGlance]. <br>
<table><tr><td colspan='2'>[[3zcm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aids_virus Aids virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZCM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZCM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PX3:5-[[[2-[(4-METHOXYPHENYL)METHYLCARBAMOYL]PHENYL]METHYL-PROP-2-ENYL-AMINO]METHYL]-1,3-BENZODIOXOLE-4-CARBOXYLIC+ACID'>PX3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PX3:5-[[[2-[(4-METHOXYPHENYL)METHYLCARBAMOYL]PHENYL]METHYL-PROP-2-ENYL-AMINO]METHYL]-1,3-BENZODIOXOLE-4-CARBOXYLIC+ACID'>PX3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zcm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zcm OCA], [http://pdbe.org/3zcm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zcm RCSB], [http://www.ebi.ac.uk/pdbsum/3zcm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zcm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zcm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zcm OCA], [https://pdbe.org/3zcm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zcm RCSB], [https://www.ebi.ac.uk/pdbsum/3zcm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zcm ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
*[[Retroviral Integrase|Retroviral Integrase]]
*[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Aids virus]]
[[Category: Aids virus]]
[[Category: Large Structures]]
[[Category: Peat, T S]]
[[Category: Peat, T S]]
[[Category: Transferase]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/3zcm"