4avc: Difference between revisions

<table><tr><td colspan='2'>[[4avc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AVC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AVC FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ava|4ava]], [[4avb|4avb]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4avc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4avc OCA], [http://pdbe.org/4avc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4avc RCSB], [http://www.ebi.ac.uk/pdbsum/4avc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4avc ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/PAT_MYCTU PAT_MYCTU]] Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS). This acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes.<ref>PMID:20507997</ref> <ref>PMID:21627103</ref> <ref>PMID:22773105</ref>