4avm: Difference between revisions
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<StructureSection load='4avm' size='340' side='right'caption='[[4avm]], [[Resolution|resolution]] 1.91Å' scene=''> | <StructureSection load='4avm' size='340' side='right'caption='[[4avm]], [[Resolution|resolution]] 1.91Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4avm]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4avm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AVM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AVM FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4avm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4avm OCA], [https://pdbe.org/4avm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4avm RCSB], [https://www.ebi.ac.uk/pdbsum/4avm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4avm ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/BIN2_HUMAN BIN2_HUMAN]] Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membrane tubulation. Plays a role in podosome formation. Inhibits phagocytosis.<ref>PMID:23285027</ref> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 05:47, 25 August 2022
Crystal structure of the N-BAR domain of human bridging integrator 2.
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