4c5x: Difference between revisions

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<StructureSection load='4c5x' size='340' side='right'caption='[[4c5x]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
<StructureSection load='4c5x' size='340' side='right'caption='[[4c5x]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4c5x]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C5X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C5X FirstGlance]. <br>
<table><tr><td colspan='2'>[[4c5x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C5X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C5X FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5HC:2-DEOXY-5-(HYDROXYMETHYL)CYTIDINE+5-(DIHYDROGEN+PHOSPHATE)'>5HC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5HC:2-DEOXY-5-(HYDROXYMETHYL)CYTIDINE+5-(DIHYDROGEN+PHOSPHATE)'>5HC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c5x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c5x OCA], [https://pdbe.org/4c5x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c5x RCSB], [https://www.ebi.ac.uk/pdbsum/4c5x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c5x ProSAT]</span></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4c63|4c63]], [[4c64|4c64]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c5x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c5x OCA], [http://pdbe.org/4c5x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4c5x RCSB], [http://www.ebi.ac.uk/pdbsum/4c5x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4c5x ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Transcription factor binding and high resolution crystallographic studies (1.3 A) of Dickerson-Drew duplexes with cytosine, methylcytosine and hydroxymethylcytosine bases provide evidence that C-5 cytosine modifications could regulate transcription by context dependent effects on DNA transcription factor interactions.
Structural insights into how 5-hydroxymethylation influences transcription factor binding.,Lercher L, McDonough MA, El-Sagheer AH, Thalhammer A, Kriaucionis S, Brown T, Schofield CJ Chem Commun (Camb). 2013 Nov 29. PMID:24287551<ref>PMID:24287551</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 4c5x" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Brown, T]]
[[Category: Synthetic construct]]
[[Category: El-Sagheer, A H]]
[[Category: Brown T]]
[[Category: McDonough, M]]
[[Category: El-Sagheer AH]]
[[Category: Schofield, C J]]
[[Category: McDonough M]]
[[Category: Cytosine modification]]
[[Category: Schofield CJ]]
[[Category: Dna]]
Retrieved from "https://proteopedia.org/4c5x"