1ia3: Difference between revisions

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[[Image:1ia3.gif|left|200px]]
[[Image:1ia3.gif|left|200px]]


{{Structure
<!--
|PDB= 1ia3 |SIZE=350|CAPTION= <scene name='initialview01'>1ia3</scene>, resolution 1.78&Aring;
The line below this paragraph, containing "STRUCTURE_1ia3", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=TQ5:5-[4-TERT-BUTYLPHENYLSULFANYL]-2,4-QUINAZOLINEDIAMINE'>TQ5</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span>
or leave the SCENE parameter empty for the default display.
|GENE= DFR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5476 Candida albicans])
-->
|DOMAIN=
{{STRUCTURE_1ia3|  PDB=1ia3 |  SCENE= }}  
|RELATEDENTRY=[[1ai9|1AI9]], [[1aoe|1AOE]], [[1ia1|1IA1]], [[1ia2|1IA2]], [[1ia4|1IA4]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ia3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ia3 OCA], [http://www.ebi.ac.uk/pdbsum/1ia3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ia3 RCSB]</span>
}}


'''Candida albicans dihydrofolate reductase complex in which the dihydronicotinamide moiety of dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) is displaced by 5-[(4-TERT-BUTYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE (GW995)'''
'''Candida albicans dihydrofolate reductase complex in which the dihydronicotinamide moiety of dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) is displaced by 5-[(4-TERT-BUTYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE (GW995)'''
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[[Category: Kuyper, L F.]]
[[Category: Kuyper, L F.]]
[[Category: Whitlow, M.]]
[[Category: Whitlow, M.]]
[[Category: antifungal target]]
[[Category: Antifungal target]]
[[Category: dihydronicotinamide displaced]]
[[Category: Dihydronicotinamide displaced]]
[[Category: oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: reductase]]
[[Category: Reductase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 19:45:35 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:16:49 2008''
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