7qy6: Difference between revisions

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====
==Structure of E.coli Class 2 L-asparaginase EcAIII, wild type (WT EcAIII)==
<StructureSection load='7qy6' size='340' side='right'caption='[[7qy6]]' scene=''>
<StructureSection load='7qy6' size='340' side='right'caption='[[7qy6]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
<table><tr><td colspan='2'>[[7qy6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QY6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QY6 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qy6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qy6 OCA], [https://pdbe.org/7qy6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qy6 RCSB], [https://www.ebi.ac.uk/pdbsum/7qy6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qy6 ProSAT]</span></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qy6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qy6 OCA], [https://pdbe.org/7qy6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qy6 RCSB], [https://www.ebi.ac.uk/pdbsum/7qy6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qy6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/IAAA_ECOLI IAAA_ECOLI]] Degrades proteins damaged by L-isoaspartyl residue formation (also known as beta-Asp residues). Degrades L-isoaspartyl-containing di- and maybe also tripeptides. Also has L-asparaginase activity, although this may not be its principal function.<ref>PMID:11988085</ref>  May be involved in glutathione, and possibly other peptide, transport, although these results could also be due to polar effects of disruption.<ref>PMID:11988085</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Z-disk]]
[[Category: Barciszewski J]]
[[Category: Bonarek P]]
[[Category: Brzezinski K]]
[[Category: Imiolczyk B]]
[[Category: Jaskolski M]]
[[Category: Kadziolka K]]
[[Category: Klonecka A]]
[[Category: Loch JI]]