7ar0: Difference between revisions
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==== | ==Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB19)== | ||
<StructureSection load='7ar0' size='340' side='right'caption='[[7ar0]]' scene=''> | <StructureSection load='7ar0' size='340' side='right'caption='[[7ar0]], [[Resolution|resolution]] 2.14Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7ar0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AR0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AR0 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ar0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ar0 OCA], [https://pdbe.org/7ar0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ar0 RCSB], [https://www.ebi.ac.uk/pdbsum/7ar0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ar0 ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ar0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ar0 OCA], [https://pdbe.org/7ar0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ar0 RCSB], [https://www.ebi.ac.uk/pdbsum/7ar0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ar0 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/VSM2_TRYBB VSM2_TRYBB]] VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Lama glama]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Trypanosoma brucei brucei]] | ||
[[Category: Hempelmann A]] | |||
[[Category: Stebbins CE]] | |||
