7u5p: Difference between revisions

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====

==CRYSTAL STRUCTURE OF THE ACTIVIN RECEPTOR TYPE-2A LIGAND BINDING DOMAIN IN COMPLEX WITH ACTIVIN-A==

== Structural highlights ==

<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance].

<table><tr><td colspan='2'>[[7u5p]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7U5P OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=7U5P FirstGlance].

</td></tr><tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=7u5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7u5p OCA], [https://pdbe.org/7u5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7u5p RCSB], [https://www.ebi.ac.uk/pdbsum/7u5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7u5p ProSAT]</td></tr>

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=7u5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7u5p OCA], [https://pdbe.org/7u5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7u5p RCSB], [https://www.ebi.ac.uk/pdbsum/7u5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7u5p ProSAT]</td></tr>

</table>

== Function ==

[[https://www.uniprot.org/uniprot/AVR2A_HUMAN AVR2A_HUMAN]] On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Z-~~disk~~]]

[[Category: Chu KY]]

[[Category: Malik A]]

[[Category: Martinez-Hackert E]]

[[Category: Thamilselvan V]]

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-====
+==CRYSTAL STRUCTURE OF THE ACTIVIN RECEPTOR TYPE-2A LIGAND BINDING DOMAIN IN COMPLEX WITH ACTIVIN-A==
-<StructureSection load='7u5p' size='340' side='right'caption='[[7u5p]]' scene=''>
+<StructureSection load='7u5p' size='340' side='right'caption='[[7u5p]], [[Resolution|resolution]] 3.14&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
+<table><tr><td colspan='2'>[[7u5p]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7U5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7U5P FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7u5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7u5p OCA], [https://pdbe.org/7u5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7u5p RCSB], [https://www.ebi.ac.uk/pdbsum/7u5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7u5p ProSAT]</span></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7u5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7u5p OCA], [https://pdbe.org/7u5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7u5p RCSB], [https://www.ebi.ac.uk/pdbsum/7u5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7u5p ProSAT]</span></td></tr>
 </table>
+== Function ==
+[[https://www.uniprot.org/uniprot/AVR2A_HUMAN AVR2A_HUMAN]] On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
 __TOC__
 </StructureSection>
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Z-disk]]
+[[Category: Chu KY]]
+[[Category: Malik A]]
+[[Category: Martinez-Hackert E]]
+[[Category: Thamilselvan V]]