7vep: Difference between revisions
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==Crystal structure and biophysical characterization of TPR domain of EccA5 from ESX-5 pathway of Mycobacterium tuberculosis H37RVR== | |||
<StructureSection load='7vep' size='340' side='right'caption='[[7vep]], [[Resolution|resolution]] 2.15Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7vep]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VEP FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vep OCA], [https://pdbe.org/7vep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vep RCSB], [https://www.ebi.ac.uk/pdbsum/7vep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vep ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Sharma | == Function == | ||
[[Category: | [[https://www.uniprot.org/uniprot/ECCA5_MYCTU ECCA5_MYCTU]] Part of the ESX-5 specialized secretion system, which is responsible for the secretion of EsxN and a number of PE_PGRS and PPE proteins, including PPE41 (PubMed:22340629, PubMed:22925462). EccA5 exhibits ATPase activity and may provide energy for the export of ESX-5 substrates (By similarity).[UniProtKB:P9WPH9]<ref>PMID:22340629</ref> <ref>PMID:22925462</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis H37Rv]] | |||
[[Category: Ramachandran R]] | |||
[[Category: Sharma VK]] | |||
[[Category: Vishwakarma J]] | |||
Revision as of 06:56, 14 September 2022
Crystal structure and biophysical characterization of TPR domain of EccA5 from ESX-5 pathway of Mycobacterium tuberculosis H37RVR
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