7zyh: Difference between revisions

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'''Unreleased structure'''


The entry 7zyh is ON HOLD  until Paper Publication
==Crystal structure of human CPSF30 in complex with hFip1==
 
<StructureSection load='7zyh' size='340' side='right'caption='[[7zyh]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
Authors: Muckenfuss, L.M., Jinek, M., Migenda Herranz, A.C., Clerici, M.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7zyh]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZYH FirstGlance]. <br>
Description: Crystal structure of human CPSF30 in complex with hFip1
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zyh OCA], [https://pdbe.org/7zyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zyh RCSB], [https://www.ebi.ac.uk/pdbsum/7zyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zyh ProSAT]</span></td></tr>
[[Category: Jinek, M]]
</table>
[[Category: Clerici, M]]
== Function ==
[[Category: Migenda Herranz, A.C]]
[[https://www.uniprot.org/uniprot/CPSF4_HUMAN CPSF4_HUMAN]] Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).<ref>PMID:9224719</ref> <ref>PMID:14749727</ref>
[[Category: Muckenfuss, L.M]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Clerici M]]
[[Category: Jinek M]]
[[Category: Migenda Herranz AC]]
[[Category: Muckenfuss LM]]

Revision as of 06:58, 14 September 2022

Crystal structure of human CPSF30 in complex with hFip1

7zyh, resolution 2.20Å

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