4ctj: Difference between revisions

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<StructureSection load='4ctj' size='340' side='right'caption='[[4ctj]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
<StructureSection load='4ctj' size='340' side='right'caption='[[4ctj]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ctj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_3 Dengue virus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CTJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CTJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ctj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_3 Dengue virus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CTJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CTJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3A9:2,3-DIHYDRO-1-BENZOFURAN-5-CARBOXYLIC+ACID'>3A9</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3A9:2,3-DIHYDRO-1-BENZOFURAN-5-CARBOXYLIC+ACID'>3A9</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ctk|4ctk]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ctj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ctj OCA], [https://pdbe.org/4ctj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ctj RCSB], [https://www.ebi.ac.uk/pdbsum/4ctj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ctj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ctj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ctj OCA], [http://pdbe.org/4ctj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ctj RCSB], [http://www.ebi.ac.uk/pdbsum/4ctj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ctj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/A9LIE0_9FLAV A9LIE0_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS013754_004_099774]  
[[https://www.uniprot.org/uniprot/A9LIE0_9FLAV A9LIE0_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS013754_004_099774]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Dengue virus 3]]
[[Category: Dengue virus 3]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Barral, K]]
[[Category: Barral K]]
[[Category: Bricogne, G]]
[[Category: Bricogne G]]
[[Category: Sharff, A]]
[[Category: Sharff A]]
[[Category: Antiviral screening]]
[[Category: Fragment-based drug discovery]]
[[Category: Ns5 methyltransferase]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/4ctj"