4cvh: Difference between revisions
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<StructureSection load='4cvh' size='340' side='right'caption='[[4cvh]], [[Resolution|resolution]] 2.39Å' scene=''> | <StructureSection load='4cvh' size='340' side='right'caption='[[4cvh]], [[Resolution|resolution]] 2.39Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4cvh]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4cvh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CVH FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cvh OCA], [https://pdbe.org/4cvh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cvh RCSB], [https://www.ebi.ac.uk/pdbsum/4cvh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cvh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
[[ | [[https://www.uniprot.org/uniprot/ISPD_HUMAN ISPD_HUMAN]] Autosomal recessive limb-girdle muscular dystrophy due to ISPD deficiency;Congenital muscular dystrophy without intellectual disability;Walker-Warburg syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/ISPD_HUMAN ISPD_HUMAN]] Required for protein O-linked mannosylation. Probably acts as a nucleotidyltransferase involved in synthesis of a nucleotide sugar. Required for dystroglycan O-mannosylation.<ref>PMID:22522420</ref> <ref>PMID:22522421</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith C]] | ||
[[Category: Bountra | [[Category: Bountra C]] | ||
[[Category: Burgess-Brown | [[Category: Burgess-Brown N]] | ||
[[Category: Edwards A]] | |||
[[Category: Edwards | [[Category: Froese DS]] | ||
[[Category: Froese | [[Category: Goubin S]] | ||
[[Category: Goubin | [[Category: Kiyani W]] | ||
[[Category: Kiyani | [[Category: Kopec J]] | ||
[[Category: Kopec | [[Category: Krojer T]] | ||
[[Category: Krojer | [[Category: Lefeber DJ]] | ||
[[Category: Lefeber | [[Category: Newman J]] | ||
[[Category: Newman | [[Category: Strain-Damerell C]] | ||
[[Category: Strain-Damerell | [[Category: Vollmar M]] | ||
[[Category: Vollmar | [[Category: Yue WW]] | ||
[[Category: Yue | [[Category: Von Delft F]] | ||
[[Category: | |||
