4cwp: Difference between revisions

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<StructureSection load='4cwp' size='340' side='right'caption='[[4cwp]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='4cwp' size='340' side='right'caption='[[4cwp]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4cwp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CWP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CWP FirstGlance]. <br>
<table><tr><td colspan='2'>[[4cwp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CWP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CWP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TV2:5-(1,3-BENZODIOXOL-5-YLMETHYL)[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-2-AMINE'>TV2</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TV2:5-(1,3-BENZODIOXOL-5-YLMETHYL)[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-2-AMINE'>TV2</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cwf|4cwf]], [[4cwn|4cwn]], [[4cwo|4cwo]], [[4cwq|4cwq]], [[4cwr|4cwr]], [[4cws|4cws]], [[4cwt|4cwt]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cwp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cwp OCA], [https://pdbe.org/4cwp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cwp RCSB], [https://www.ebi.ac.uk/pdbsum/4cwp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cwp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cwp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cwp OCA], [http://pdbe.org/4cwp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cwp RCSB], [http://www.ebi.ac.uk/pdbsum/4cwp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cwp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>
[[https://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Amboldi, N]]
[[Category: Amboldi N]]
[[Category: Brasca, G]]
[[Category: Brasca G]]
[[Category: Caronni, D]]
[[Category: Caronni D]]
[[Category: Casale, E]]
[[Category: Casale E]]
[[Category: Casuscelli, F]]
[[Category: Casuscelli F]]
[[Category: Colombo, N]]
[[Category: Colombo N]]
[[Category: Dalvit, C]]
[[Category: Dalvit C]]
[[Category: Felder, E R]]
[[Category: Felder ER]]
[[Category: Fogliatto, G]]
[[Category: Fogliatto G]]
[[Category: Isacchi, A]]
[[Category: Isacchi A]]
[[Category: Mantegani, S]]
[[Category: Mantegani S]]
[[Category: Polucci, P]]
[[Category: Polucci P]]
[[Category: Riceputi, L]]
[[Category: Riceputi L]]
[[Category: Sola, F]]
[[Category: Sola F]]
[[Category: Visco, C]]
[[Category: Visco C]]
[[Category: Zuccotto, F]]
[[Category: Zuccotto F]]
[[Category: Chaperone]]