4d61: Difference between revisions

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<SX load='4d61' size='340' side='right' viewer='molstar' caption='[[4d61]], [[Resolution|resolution]] 9.00&Aring;' scene=''>
<SX load='4d61' size='340' side='right' viewer='molstar' caption='[[4d61]], [[Resolution|resolution]] 9.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4d61]] is a 37 chain structure with sequence from [http://en.wikipedia.org/wiki/European_rabbit European rabbit] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D61 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4D61 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4d61]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D61 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D61 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4d61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d61 OCA], [http://pdbe.org/4d61 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d61 RCSB], [http://www.ebi.ac.uk/pdbsum/4d61 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4d61 ProSAT]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d61 OCA], [https://pdbe.org/4d61 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d61 RCSB], [https://www.ebi.ac.uk/pdbsum/4d61 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d61 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ERF1_HUMAN ERF1_HUMAN]] Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.<ref>PMID:7990965</ref>  [[http://www.uniprot.org/uniprot/ERF3A_HUMAN ERF3A_HUMAN]] Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  
[[https://www.uniprot.org/uniprot/G1TWL4_RABIT G1TWL4_RABIT]] Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.[HAMAP-Rule:MF_03016]
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Receptor for activated protein kinase C 1|Receptor for activated protein kinase C 1]]
*[[3D sructureseceptor for activated protein kinase C 1|3D sructureseceptor for activated protein kinase C 1]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</SX>
</SX>
[[Category: European rabbit]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Hilal, T]]
[[Category: Hilal T]]
[[Category: Mielke, T]]
[[Category: Mielke T]]
[[Category: Muhs, M]]
[[Category: Muhs M]]
[[Category: Pestova, T V]]
[[Category: Pestova TV]]
[[Category: Sanbonmatsu, K Y]]
[[Category: Sanbonmatsu KY]]
[[Category: Skabkin, M A]]
[[Category: Skabkin MA]]
[[Category: Spahn, C M.T]]
[[Category: Spahn CMT]]
[[Category: Crpv ire]]
[[Category: Release factor]]
[[Category: Ribosome]]
[[Category: Termination]]
Retrieved from "https://proteopedia.org/4d61"