4d6s: Difference between revisions

<table><tr><td colspan='2'>[[4d6s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D6S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D6S FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMD:5,6-DIMETHYLBENZIMIDAZOLE'>DMD</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d6s OCA], [https://pdbe.org/4d6s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d6s RCSB], [https://www.ebi.ac.uk/pdbsum/4d6s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d6s ProSAT]</span></td></tr>

[[https://www.uniprot.org/uniprot/KDM4D_HUMAN KDM4D_HUMAN]] Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.<ref>PMID:16603238</ref>  

[[Category: Homo sapiens]]

[[Category: Arrowsmith CH]]

[[Category: Bountra C]]

[[Category: Bradley A]]

[[Category: Burgess-Brown N]]

[[Category: Crawley L]]

[[Category: Edwards A]]

[[Category: Gileadi C]]

[[Category: Johansson C]]

[[Category: Krojer T]]

[[Category: Oppermann U]]

[[Category: Szykowska A]]

[[Category: Vollmar M]]

[[Category: Von Delft F]]