4d8a: Difference between revisions

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==Crystal structure of B. anthracis DHPS with compound 21==
==Crystal structure of B. anthracis DHPS with compound 21==
<StructureSection load='4d8a' size='340' side='right' caption='[[4d8a]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
<StructureSection load='4d8a' size='340' side='right'caption='[[4d8a]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4d8a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_a2012 Bacillus anthracis a2012]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D8A FirstGlance]. <br>
<table><tr><td colspan='2'>[[4d8a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._A2012 Bacillus anthracis str. A2012]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D8A FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0HY:METHYL+(3R)-3-(7-AMINO-4,5-DIOXO-1,4,5,6-TETRAHYDROPYRIMIDO[4,5-C]PYRIDAZIN-3-YL)BUTANOATE'>0HY</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0HY:METHYL+(3R)-3-(7-AMINO-4,5-DIOXO-1,4,5,6-TETRAHYDROPYRIMIDO[4,5-C]PYRIDAZIN-3-YL)BUTANOATE'>0HY</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tws|1tws]], [[4d8z|4d8z]], [[4d9p|4d9p]], [[4daf|4daf]], [[4dai|4dai]], [[4db7|4db7]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d8a OCA], [https://pdbe.org/4d8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d8a RCSB], [https://www.ebi.ac.uk/pdbsum/4d8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d8a ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=191218 Bacillus anthracis A2012])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydropteroate_synthase Dihydropteroate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.15 2.5.1.15] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d8a OCA], [http://pdbe.org/4d8a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d8a RCSB], [http://www.ebi.ac.uk/pdbsum/4d8a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4d8a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/C3P9L8_BACAA C3P9L8_BACAA]] DHPS catalyzes the formation of the immediate precursor of folic acid.[RuleBase:RU361205]  
[[https://www.uniprot.org/uniprot/Q81VW8_BACAN Q81VW8_BACAN]]  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4d8a" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4d8a" style="background-color:#fffaf0;"></div>
==See Also==
*[[Dihydropteroate synthase 3D structures|Dihydropteroate synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus anthracis a2012]]
[[Category: Bacillus anthracis str. A2012]]
[[Category: Dihydropteroate synthase]]
[[Category: Large Structures]]
[[Category: Hammoudeh, D]]
[[Category: Hammoudeh D]]
[[Category: Lee, R E]]
[[Category: Lee RE]]
[[Category: White, S W]]
[[Category: White SW]]
[[Category: Synthase]]
[[Category: Tim barrel]]
[[Category: Tim narrel]]
[[Category: Transferase-transferase inhibitor complex]]
Retrieved from "https://proteopedia.org/4d8a"