1rd9: Difference between revisions

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<StructureSection load='1rd9' size='340' side='right'caption='[[1rd9]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
<StructureSection load='1rd9' size='340' side='right'caption='[[1rd9]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1rd9]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillo_virgola_del_koch"_trevisan_1884 "bacillo virgola del koch" trevisan 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RD9 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1RD9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1rd9]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RD9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RD9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BV2:1,3-BIS-([3-(4-{3-[3-NITRO-5-(GALACTOPYRANOSYLOXY)-BENZOYLAMINO]-PROPYL}-PIPERAZIN-1-YL)-PROPYL-AMINO]-CARBONYLOXY)-2-AMINO-PROPANE'>BV2</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BV2:1,3-BIS-([3-(4-{3-[3-NITRO-5-(GALACTOPYRANOSYLOXY)-BENZOYLAMINO]-PROPYL}-PIPERAZIN-1-YL)-PROPYL-AMINO]-CARBONYLOXY)-2-AMINO-PROPANE'>BV2</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1rcv|1rcv]], [[1rdp|1rdp]], [[1rf2|1rf2]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rd9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rd9 OCA], [https://pdbe.org/1rd9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rd9 RCSB], [https://www.ebi.ac.uk/pdbsum/1rd9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rd9 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ctxB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 "Bacillo virgola del Koch" Trevisan 1884])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1rd9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rd9 OCA], [http://pdbe.org/1rd9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1rd9 RCSB], [http://www.ebi.ac.uk/pdbsum/1rd9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1rd9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CHTB_VIBCH CHTB_VIBCH]] The B subunit pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself.  
[[https://www.uniprot.org/uniprot/CHTB_VIBCH CHTB_VIBCH]] The B subunit pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillo virgola del koch trevisan 1884]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Fan, E]]
[[Category: Vibrio cholerae]]
[[Category: Hol, W G]]
[[Category: Fan E]]
[[Category: Liu, J]]
[[Category: Hol WG]]
[[Category: Mitchell, D D]]
[[Category: Liu J]]
[[Category: Pickens, J C]]
[[Category: Mitchell DD]]
[[Category: Tan, X]]
[[Category: Pickens JC]]
[[Category: Verlinde, C L]]
[[Category: Tan X]]
[[Category: Zhang, Z]]
[[Category: Verlinde CL]]
[[Category: Bivalent]]
[[Category: Zhang Z]]
[[Category: Cholera]]
[[Category: Complex]]
[[Category: Pentamer]]
[[Category: Toxin]]
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