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==Crystal Structure of methyltransferase RlmG modifying G1835 of 23S rRNA in Escherichia coli==
==Crystal Structure of methyltransferase RlmG modifying G1835 of 23S rRNA in Escherichia coli==
<StructureSection load='4dcm' size='340' side='right' caption='[[4dcm]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='4dcm' size='340' side='right'caption='[[4dcm]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4dcm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DCM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DCM FirstGlance]. <br>
<table><tr><td colspan='2'>[[4dcm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DCM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DCM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dcm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dcm OCA], [https://pdbe.org/4dcm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dcm RCSB], [https://www.ebi.ac.uk/pdbsum/4dcm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dcm ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b3084, JW5513, rlmG, ygjO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/23S_rRNA_(guanine(1835)-N(2))-methyltransferase 23S rRNA (guanine(1835)-N(2))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.174 2.1.1.174] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dcm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dcm OCA], [http://pdbe.org/4dcm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4dcm RCSB], [http://www.ebi.ac.uk/pdbsum/4dcm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4dcm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RLMG_ECOLI RLMG_ECOLI]] Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.<ref>PMID:17010380</ref>
[[https://www.uniprot.org/uniprot/RLMG_ECOLI RLMG_ECOLI]] Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.<ref>PMID:17010380</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Dong, Y H]]
[[Category: Large Structures]]
[[Category: Gao, Z Q]]
[[Category: Dong YH]]
[[Category: Zhang, H]]
[[Category: Gao ZQ]]
[[Category: Transferase]]
[[Category: Zhang H]]
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