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==Crystal structure of aminoglycoside phosphotransferase APH(2")-Id/APH(2")-IVa in complex with HEPES==
==Crystal structure of aminoglycoside phosphotransferase APH(2")-Id/APH(2")-IVa in complex with HEPES==
<StructureSection load='4de4' size='340' side='right' caption='[[4de4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='4de4' size='340' side='right'caption='[[4de4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4de4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptococcus_casseliflavus"_vaughan_et_al._1979 "streptococcus casseliflavus" vaughan et al. 1979]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3r80 3r80]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DE4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DE4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4de4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_casseliflavus Enterococcus casseliflavus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3r80 3r80]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DE4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4de4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4de4 OCA], [https://pdbe.org/4de4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4de4 RCSB], [https://www.ebi.ac.uk/pdbsum/4de4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4de4 ProSAT]</span></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3r7z|3r7z]], [[3r81|3r81]], [[3r82|3r82]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aph(2")-Id ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=37734 "Streptococcus casseliflavus" Vaughan et al. 1979])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4de4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4de4 OCA], [http://pdbe.org/4de4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4de4 RCSB], [http://www.ebi.ac.uk/pdbsum/4de4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4de4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/O68183_ENTCA O68183_ENTCA]]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Phosphotransferase|Phosphotransferase]]
*[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Streptococcus casseliflavus vaughan et al. 1979]]
[[Category: Enterococcus casseliflavus]]
[[Category: Anderson, W F]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Anderson WF]]
[[Category: Egorova, O]]
[[Category: Di Leo R]]
[[Category: Evdokimova, E]]
[[Category: Egorova O]]
[[Category: Leo, R Di]]
[[Category: Evdokimova E]]
[[Category: Li, H]]
[[Category: Li H]]
[[Category: Minasov, G]]
[[Category: Minasov G]]
[[Category: Nocek, B]]
[[Category: Nocek B]]
[[Category: Savchenko, A]]
[[Category: Savchenko A]]
[[Category: Stogios, P J]]
[[Category: Stogios PJ]]
[[Category: Tan, K]]
[[Category: Tan K]]
[[Category: Aminoglycoside phosphotransferase]]
[[Category: Aminoglycoside]]
[[Category: Csgid]]
[[Category: Eukaryotic protein kinase-like fold]]
[[Category: Intracellular]]
[[Category: Kinase]]
[[Category: National institute of allergy and infectious disease]]
[[Category: Niaid]]
[[Category: Transferase]]
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