7vh9: Difference between revisions

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'''Unreleased structure'''


The entry 7vh9 is ON HOLD  until Paper Publication
==Solution structure of the chimeric peptide of the first SURP domain of Human SF3A1 and the interacting region of SF1.==
 
<StructureSection load='7vh9' size='340' side='right'caption='[[7vh9]]' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7vh9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VH9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VH9 FirstGlance]. <br>
Description:  
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vh9 OCA], [https://pdbe.org/7vh9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vh9 RCSB], [https://www.ebi.ac.uk/pdbsum/7vh9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vh9 ProSAT]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
== Function ==
[[https://www.uniprot.org/uniprot/SF3A1_HUMAN SF3A1_HUMAN]] Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.[[https://www.uniprot.org/uniprot/SF01_HUMAN SF01_HUMAN]] Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.<ref>PMID:8752089</ref> <ref>PMID:10449420</ref> <ref>PMID:9660765</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Kobayashi N]]
[[Category: Kuwasako K]]
[[Category: Muto Y]]
[[Category: Sakamoto T]]
[[Category: Takizawa M]]
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