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==Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis at 1.62A resolution==
==Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis at 1.62A resolution==
<StructureSection load='4e1a' size='340' side='right' caption='[[4e1a]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
<StructureSection load='4e1a' size='340' side='right'caption='[[4e1a]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4e1a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E1A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E1A FirstGlance]. <br>
<table><tr><td colspan='2'>[[4e1a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E1A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E1A FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">coaD, kdtB, Rv2965c, MT3043, MTCY349.22, u0002e ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e1a OCA], [https://pdbe.org/4e1a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e1a RCSB], [https://www.ebi.ac.uk/pdbsum/4e1a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e1a ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantetheine-phosphate_adenylyltransferase Pantetheine-phosphate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.3 2.7.7.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e1a OCA], [http://pdbe.org/4e1a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4e1a RCSB], [http://www.ebi.ac.uk/pdbsum/4e1a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4e1a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/COAD_MYCTU COAD_MYCTU]] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).  
[[https://www.uniprot.org/uniprot/COAD_MYCTU COAD_MYCTU]] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pantetheine-phosphate adenylyltransferase]]
[[Category: Large Structures]]
[[Category: Chupova, L A]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Esipov, R S]]
[[Category: Chupova LA]]
[[Category: Kuranova, I P]]
[[Category: Esipov RS]]
[[Category: Smirnova, E A]]
[[Category: Kuranova IP]]
[[Category: Timofeev, V I]]
[[Category: Smirnova EA]]
[[Category: Transferase]]
[[Category: Timofeev VI]]

Revision as of 06:44, 28 September 2022

Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis at 1.62A resolution

4e1a, resolution 1.62Å

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