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==Human histidine decarboxylase complex with Histidine methyl ester (HME)==
==Human histidine decarboxylase complex with Histidine methyl ester (HME)==
<StructureSection load='4e1o' size='340' side='right' caption='[[4e1o]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4e1o' size='340' side='right'caption='[[4e1o]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4e1o]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E1O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E1O FirstGlance]. <br>
<table><tr><td colspan='2'>[[4e1o]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E1O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E1O FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PVH:HISTIDINE-METHYL-ESTER'>PVH</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PVH:HISTIDINE-METHYL-ESTER'>PVH</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e1o OCA], [https://pdbe.org/4e1o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e1o RCSB], [https://www.ebi.ac.uk/pdbsum/4e1o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e1o ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HDC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_decarboxylase Histidine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.22 4.1.1.22] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e1o OCA], [http://pdbe.org/4e1o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4e1o RCSB], [http://www.ebi.ac.uk/pdbsum/4e1o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4e1o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DCHS_HUMAN DCHS_HUMAN]] Catalyzes the biosynthesis of histamine from histidine.<ref>PMID:22767596</ref>
[[https://www.uniprot.org/uniprot/DCHS_HUMAN DCHS_HUMAN]] Catalyzes the biosynthesis of histamine from histidine.<ref>PMID:22767596</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Histidine decarboxylase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Higuchi, Y]]
[[Category: Higuchi Y]]
[[Category: Komori, H]]
[[Category: Komori H]]
[[Category: Nitta, Y]]
[[Category: Nitta Y]]
[[Category: Ueno, H]]
[[Category: Ueno H]]
[[Category: Lyase]]
Retrieved from "https://proteopedia.org/4e1o"