4e6s: Difference between revisions

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==Crystal structure of the SCAN domain from mouse Zfp206==
==Crystal structure of the SCAN domain from mouse Zfp206==
<StructureSection load='4e6s' size='340' side='right' caption='[[4e6s]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='4e6s' size='340' side='right'caption='[[4e6s]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4e6s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E6S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E6S FirstGlance]. <br>
<table><tr><td colspan='2'>[[4e6s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E6S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E6S FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3lhr|3lhr]], [[2fi2|2fi2]], [[1y7q|1y7q]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e6s OCA], [https://pdbe.org/4e6s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e6s RCSB], [https://www.ebi.ac.uk/pdbsum/4e6s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e6s ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Zscan10, Zfp206 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e6s OCA], [http://pdbe.org/4e6s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4e6s RCSB], [http://www.ebi.ac.uk/pdbsum/4e6s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4e6s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/ZSC10_MOUSE ZSC10_MOUSE]] Embryonic stem (ES) cell-specific transcription factor required to maintain ES cell pluripotency. Can both activate and /or repress expression of target genes, depending on the context. Specifically binds the 5'-[GA]CGCNNGCG[CT]-3' DNA consensus sequence. Regulates expression of POU5F1/OCT4, ZSCAN4 and ALYREF/THOC4.<ref>PMID:16971461</ref> <ref>PMID:17628018</ref> <ref>PMID:19740739</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Baburajendran, N]]
[[Category: Mus musculus]]
[[Category: Choo, S H]]
[[Category: Baburajendran N]]
[[Category: Kolatkar, P R]]
[[Category: Choo SH]]
[[Category: Liang, Y]]
[[Category: Kolatkar PR]]
[[Category: Palasingam, P]]
[[Category: Liang Y]]
[[Category: Rossbach, M]]
[[Category: Palasingam P]]
[[Category: N-terminal part]]
[[Category: Rossbach M]]
[[Category: Other scan]]
[[Category: Protein interaction]]
[[Category: Scan domain]]
[[Category: Transcription]]
[[Category: Zinc finger transcription factor]]
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