1iyk: Difference between revisions

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<StructureSection load='1iyk' size='340' side='right'caption='[[1iyk]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1iyk' size='340' side='right'caption='[[1iyk]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1iyk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_11006_[[candida_stellatoidea]] Atcc 11006 [[candida stellatoidea]]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IYK FirstGlance]. <br>
<table><tr><td colspan='2'>[[1iyk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IYK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MIM:[CYCLOHEXYLETHYL]-[[[[4-[2-METHYL-1-IMIDAZOLYL-BUTYL]PHENYL]ACETYL]-SERYL]-LYSINYL]-AMINE'>MIM</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MIM:[CYCLOHEXYLETHYL]-[[[[4-[2-METHYL-1-IMIDAZOLYL-BUTYL]PHENYL]ACETYL]-SERYL]-LYSINYL]-AMINE'>MIM</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1iyl|1iyl]]</div></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iyk OCA], [https://pdbe.org/1iyk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iyk RCSB], [https://www.ebi.ac.uk/pdbsum/1iyk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iyk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iyk OCA], [https://pdbe.org/1iyk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iyk RCSB], [https://www.ebi.ac.uk/pdbsum/1iyk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iyk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/NMT_CANAL NMT_CANAL]] Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. Substrate specificity requires an N-terminal glycine in the nascent polypeptide substrates. Ser is present at position 5 in almost all known N-myristoyl proteins and Lys is commonly encountered at postion 6. Basic residues are preferred at positions 7 and 8.<ref>PMID:1569105</ref> <ref>PMID:8300631</ref> <ref>PMID:9115247</ref>
[https://www.uniprot.org/uniprot/NMT_CANAL NMT_CANAL] Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. Substrate specificity requires an N-terminal glycine in the nascent polypeptide substrates. Ser is present at position 5 in almost all known N-myristoyl proteins and Lys is commonly encountered at postion 6. Basic residues are preferred at positions 7 and 8.<ref>PMID:1569105</ref> <ref>PMID:8300631</ref> <ref>PMID:9115247</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Glycylpeptide N-tetradecanoyltransferase]]
[[Category: Candida albicans]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Aoki, Y]]
[[Category: Aoki Y]]
[[Category: Arcy, A D]]
[[Category: Banner DW]]
[[Category: Banner, D W]]
[[Category: D'Arcy A]]
[[Category: Fukami, T A]]
[[Category: Fukami TA]]
[[Category: Morikami, K]]
[[Category: Morikami K]]
[[Category: Ohtsuka, T]]
[[Category: Ohtsuka T]]
[[Category: Shiratori, Y]]
[[Category: Shiratori Y]]
[[Category: Sogabe, S]]
[[Category: Sogabe S]]
[[Category: Winkler, F K]]
[[Category: Winkler FK]]
[[Category: Transferase]]
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