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==Crystal structure of multidrug-resistant clinical isolate 769 HIV-1 protease in complex with ritonavir==
==Crystal structure of multidrug-resistant clinical isolate 769 HIV-1 protease in complex with ritonavir==
<StructureSection load='4eyr' size='340' side='right' caption='[[4eyr]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4eyr' size='340' side='right'caption='[[4eyr]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4eyr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EYR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EYR FirstGlance]. <br>
<table><tr><td colspan='2'>[[4eyr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EYR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EYR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RIT:RITONAVIR'>RIT</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RIT:RITONAVIR'>RIT</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tw7|1tw7]], [[3oq7|3oq7]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eyr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eyr OCA], [https://pdbe.org/4eyr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eyr RCSB], [https://www.ebi.ac.uk/pdbsum/4eyr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eyr ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eyr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eyr OCA], [http://pdbe.org/4eyr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4eyr RCSB], [http://www.ebi.ac.uk/pdbsum/4eyr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4eyr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q000H7_9HIV1 Q000H7_9HIV1]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Immunodeficiency virus protease|Immunodeficiency virus protease]]
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Brunzelle, J S]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Kovari, I A]]
[[Category: Large Structures]]
[[Category: Kovari, L C]]
[[Category: Brunzelle JS]]
[[Category: Liu, Z]]
[[Category: Kovari IA]]
[[Category: Wang, Y]]
[[Category: Kovari LC]]
[[Category: Yedidi, R S]]
[[Category: Liu Z]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Wang Y]]
[[Category: Protease]]
[[Category: Yedidi RS]]

Revision as of 04:23, 7 October 2022

Crystal structure of multidrug-resistant clinical isolate 769 HIV-1 protease in complex with ritonavir

4eyr, resolution 1.80Å

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