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==Crystal structure of Thymidylate Kinase from Staphylococcus aureus in apo-form==
==Crystal structure of Thymidylate Kinase from Staphylococcus aureus in apo-form==
<StructureSection load='4f4i' size='340' side='right' caption='[[4f4i]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
<StructureSection load='4f4i' size='340' side='right'caption='[[4f4i]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4f4i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staam Staam]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F4I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4F4I FirstGlance]. <br>
<table><tr><td colspan='2'>[[4f4i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F4I FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dwj|4dwj]], [[4eaq|4eaq]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f4i OCA], [https://pdbe.org/4f4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f4i RCSB], [https://www.ebi.ac.uk/pdbsum/4f4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f4i ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tmk, SAV0482 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 STAAM])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4f4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f4i OCA], [http://pdbe.org/4f4i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4f4i RCSB], [http://www.ebi.ac.uk/pdbsum/4f4i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4f4i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KTHY_STAAM KTHY_STAAM]] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity).  
[https://www.uniprot.org/uniprot/KTHY_STAAM KTHY_STAAM] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity).
 
==See Also==
*[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Staam]]
[[Category: Large Structures]]
[[Category: DTMP kinase]]
[[Category: Staphylococcus aureus subsp. aureus Mu50]]
[[Category: Anderson, W F]]
[[Category: Anderson WF]]
[[Category: Babnigg, G]]
[[Category: Babnigg G]]
[[Category: Filippova, E V]]
[[Category: Filippova EV]]
[[Category: Jedrzejczak, R]]
[[Category: Jedrzejczak R]]
[[Category: Joachimiak, A]]
[[Category: Joachimiak A]]
[[Category: Kiryukhina, O]]
[[Category: Kiryukhina O]]
[[Category: Structural genomic]]
[[Category: Minasov G]]
[[Category: MTBI, Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors]]
[[Category: Rubin E]]
[[Category: Minasov, G]]
[[Category: Sacchettini J]]
[[Category: Rubin, E]]
[[Category: Shuvalova L]]
[[Category: Sacchettini, J]]
[[Category: Shuvalova, L]]
[[Category: Mcsg]]
[[Category: Psi-biology]]
[[Category: Thymidylate kinase]]
[[Category: Transferase]]

Revision as of 04:34, 7 October 2022

Crystal structure of Thymidylate Kinase from Staphylococcus aureus in apo-form

4f4i, resolution 2.45Å

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