7wtw: Difference between revisions
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The entry | ==Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A3== | ||
<StructureSection load='7wtw' size='340' side='right'caption='[[7wtw]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7wtw]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WTW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WTW FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G7M:N7-METHYL-GUANOSINE-5-MONOPHOSPHATE'>G7M</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wtw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wtw OCA], [https://pdbe.org/7wtw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wtw RCSB], [https://www.ebi.ac.uk/pdbsum/7wtw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wtw ProSAT]</span></td></tr> | ||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/RS17_HUMAN RS17_HUMAN] Blackfan-Diamond disease. Diamond-Blackfan anemia 4 (DBA4) [MIM:[https://omim.org/entry/612527 612527]: A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of developing leukemia. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:17647292</ref> <ref>PMID:19061985</ref> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RS17_HUMAN RS17_HUMAN] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Ameismeier M]] | |||
[[Category: Beckmann R]] | |||
[[Category: Berninghausen O]] | |||
[[Category: Cheng J]] | |||
[[Category: Hurt E]] | |||
[[Category: Lau B]] | |||
[[Category: Thoms M]] | |||
Latest revision as of 19:23, 19 October 2022
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A3
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