4g89: Difference between revisions

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==Crystal structure of k. pneumoniae mta/adohcy nucleosidase in complex with fragmented s-adenosyl-l-homocysteine==
==Crystal structure of k. pneumoniae mta/adohcy nucleosidase in complex with fragmented s-adenosyl-l-homocysteine==
<StructureSection load='4g89' size='340' side='right' caption='[[4g89]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='4g89' size='340' side='right'caption='[[4g89]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4g89]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Klep7 Klep7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G89 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4G89 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4g89]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae_MGH_78578 Klebsiella pneumoniae subsp. pneumoniae MGH 78578]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G89 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KPN 00174, KPN78578_01730, KPN_00174, mtnN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272620 KLEP7])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g89 OCA], [https://pdbe.org/4g89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g89 RCSB], [https://www.ebi.ac.uk/pdbsum/4g89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g89 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylhomocysteine_nucleosidase Adenosylhomocysteine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.9 3.2.2.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g89 OCA], [http://pdbe.org/4g89 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4g89 RCSB], [http://www.ebi.ac.uk/pdbsum/4g89 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4g89 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MTNN_KLEP7 MTNN_KLEP7]] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity).  
[https://www.uniprot.org/uniprot/MTNN_KLEP7 MTNN_KLEP7] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Adenosylhomocysteine nucleosidase]]
[[Category: Klebsiella pneumoniae subsp. pneumoniae MGH 78578]]
[[Category: Klep7]]
[[Category: Large Structures]]
[[Category: Anderson, B F]]
[[Category: Anderson BF]]
[[Category: Brown, R L]]
[[Category: Brown RL]]
[[Category: Evans, G B]]
[[Category: Evans GB]]
[[Category: Norris, G E]]
[[Category: Norris GE]]
[[Category: Tyler, P C]]
[[Category: Tyler PC]]
[[Category: Cleavage]]
[[Category: Dimer]]
[[Category: Hydrolase]]
[[Category: Mixed alpha/beta]]
[[Category: S-adenosylhomocysteine]]
Retrieved from "https://proteopedia.org/4g89"