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==Crystal Structure of E. coli OmpF porin in complex with Ampicillin==
==Crystal Structure of E. coli OmpF porin in complex with Ampicillin==
<StructureSection load='4gcp' size='340' side='right' caption='[[4gcp]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
<StructureSection load='4gcp' size='340' side='right'caption='[[4gcp]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4gcp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GCP FirstGlance]. <br>
<table><tr><td colspan='2'>[[4gcp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GCP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AIC:(2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC+ACID'>AIC</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AIC:(2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC+ACID'>AIC</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gcq|4gcq]], [[4gcs|4gcs]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gcp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gcp OCA], [https://pdbe.org/4gcp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gcp RCSB], [https://www.ebi.ac.uk/pdbsum/4gcp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gcp ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ompF, cmlB, coa, cry, tolF, b0929, JW0912 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gcp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gcp OCA], [http://pdbe.org/4gcp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gcp RCSB], [http://www.ebi.ac.uk/pdbsum/4gcp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gcp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/OMPF_ECOLI OMPF_ECOLI]] Forms pores that allow passive diffusion of small molecules across the outer membrane. It is also a receptor for the bacteriophage T2.<ref>PMID:19721064</ref>
[https://www.uniprot.org/uniprot/OMPF_ECOLI OMPF_ECOLI] Forms pores that allow passive diffusion of small molecules across the outer membrane. It is also a receptor for the bacteriophage T2.<ref>PMID:19721064</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Porin|Porin]]
*[[Porin 3D structures|Porin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Roux, B]]
[[Category: Large Structures]]
[[Category: Ziervogel, B K]]
[[Category: Roux B]]
[[Category: Ampicillin binding]]
[[Category: Ziervogel BK]]
[[Category: Beta-barrel]]
[[Category: Membrane protein-antibiotic complex]]
[[Category: Non-specific channel]]
[[Category: Outer membrane]]
[[Category: Protein-drug complex]]
[[Category: Trimer]]
Retrieved from "https://proteopedia.org/4gcp"