4gfv: Difference between revisions
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==PTPN18 in complex with HER2-pY1196 phosphor-peptides== | ==PTPN18 in complex with HER2-pY1196 phosphor-peptides== | ||
<StructureSection load='4gfv' size='340' side='right' caption='[[4gfv]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='4gfv' size='340' side='right'caption='[[4gfv]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4gfv]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4gfv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GFV FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gfv OCA], [https://pdbe.org/4gfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gfv RCSB], [https://www.ebi.ac.uk/pdbsum/4gfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gfv ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PTN18_HUMAN PTN18_HUMAN] Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues. | ||
==See Also== | ==See Also== | ||
*[[Tyrosine phosphatase|Tyrosine phosphatase]] | *[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Du | [[Category: Du YJ]] | ||
[[Category: Sun | [[Category: Sun JP]] | ||
[[Category: Wang | [[Category: Wang HM]] | ||
[[Category: Yang | [[Category: Yang DX]] | ||
[[Category: Yang | [[Category: Yang F]] | ||
[[Category: Yu | [[Category: Yu X]] | ||
[[Category: Zhang | [[Category: Zhang Y]] | ||
Revision as of 06:54, 26 October 2022
PTPN18 in complex with HER2-pY1196 phosphor-peptides
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