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==Structural Basis for Marburg virus VP35 mediate immune evasion mechanisms==
==Structural Basis for Marburg virus VP35 mediate immune evasion mechanisms==
<StructureSection load='4ghl' size='340' side='right' caption='[[4ghl]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
<StructureSection load='4ghl' size='340' side='right'caption='[[4ghl]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ghl]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Lake_victoria_marburg_virus_-_popp Lake victoria marburg virus - popp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GHL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GHL FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ghl]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Lake_Victoria_marburgvirus_-_Popp Lake Victoria marburgvirus - Popp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GHL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GHL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fke|3fke]], [[3l25|3l25]], [[3l26|3l26]], [[3l27|3l27]], [[3l28|3l28]], [[3l29|3l29]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ghl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ghl OCA], [https://pdbe.org/4ghl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ghl RCSB], [https://www.ebi.ac.uk/pdbsum/4ghl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ghl ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Polymerase cofactor VP35, VP35 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33728 Lake Victoria marburg virus - Popp])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ghl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ghl OCA], [http://pdbe.org/4ghl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ghl RCSB], [http://www.ebi.ac.uk/pdbsum/4ghl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ghl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/VP35_MABVP VP35_MABVP]] Acts as a polymerase cofactor in the RNA polymerase transcription and replication complex.  
[https://www.uniprot.org/uniprot/VP35_MABVP VP35_MABVP] Acts as a polymerase cofactor in the RNA polymerase transcription and replication complex.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lake victoria marburg virus - popp]]
[[Category: Lake Victoria marburgvirus - Popp]]
[[Category: Amarasinghe, G K]]
[[Category: Large Structures]]
[[Category: Borek, D M]]
[[Category: Amarasinghe GK]]
[[Category: Leung, D W]]
[[Category: Borek DM]]
[[Category: Otwinowski, Z]]
[[Category: Leung DW]]
[[Category: Ramanan, P]]
[[Category: Otwinowski Z]]
[[Category: Double stranded rna]]
[[Category: Ramanan P]]
[[Category: Ifn inhibitor]]
[[Category: Interferon antagonism]]
[[Category: Protein-rna complex]]
[[Category: Rna binding protein]]
[[Category: Transcription]]
[[Category: Viral protein-rna complex]]
[[Category: Vp35]]
Retrieved from "https://proteopedia.org/4ghl"