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==Crystal structure of methylthioadenosine phosphorylase sourced from an antarctic soil metagenomic library==
==Crystal structure of methylthioadenosine phosphorylase sourced from an antarctic soil metagenomic library==
<StructureSection load='4glf' size='340' side='right' caption='[[4glf]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
<StructureSection load='4glf' size='340' side='right'caption='[[4glf]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4glf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacterial_sp. Bacterial sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GLF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GLF FirstGlance]. <br>
<table><tr><td colspan='2'>[[4glf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Uncultured_bacterium Uncultured bacterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GLF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GLF FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rsfP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=77133 Bacterial sp.])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4glf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4glf OCA], [https://pdbe.org/4glf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4glf RCSB], [https://www.ebi.ac.uk/pdbsum/4glf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4glf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4glf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4glf OCA], [http://pdbe.org/4glf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4glf RCSB], [http://www.ebi.ac.uk/pdbsum/4glf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4glf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/C6KFA4_9BACT C6KFA4_9BACT]] Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.[HAMAP-Rule:MF_01963]  
[https://www.uniprot.org/uniprot/C6KFA4_9BACT C6KFA4_9BACT] Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.[HAMAP-Rule:MF_01963]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[5'-deoxy-5'-methylthioadenosine phosphorylase|5'-deoxy-5'-methylthioadenosine phosphorylase]]
*[[5'-deoxy-5'-methylthioadenosine phosphorylase 3D structures|5'-deoxy-5'-methylthioadenosine phosphorylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacterial sp]]
[[Category: Large Structures]]
[[Category: Bartasun, P]]
[[Category: Uncultured bacterium]]
[[Category: Bujacz, A]]
[[Category: Bartasun P]]
[[Category: Bujacz, G]]
[[Category: Bujacz A]]
[[Category: Cieslinski, H]]
[[Category: Bujacz G]]
[[Category: Metagenomic library antarctic soil]]
[[Category: Cieslinski H]]
[[Category: Methylthioadenosine]]
[[Category: Methylthioadenosine phosphorylase]]
[[Category: Rhodamine b]]
[[Category: Transferase]]
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