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==Crystal structure of HisB from Mycobacterium tuberculosis==
==Crystal structure of HisB from Mycobacterium tuberculosis==
<StructureSection load='4gqu' size='340' side='right' caption='[[4gqu]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
<StructureSection load='4gqu' size='340' side='right'caption='[[4gqu]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4gqu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GQU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GQU FirstGlance]. <br>
<table><tr><td colspan='2'>[[4gqu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GQU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GQU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2f1d|2f1d]], [[1rhy|1rhy]], [[4lpf|4lpf]], [[4lom|4lom]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gqu OCA], [https://pdbe.org/4gqu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gqu RCSB], [https://www.ebi.ac.uk/pdbsum/4gqu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gqu ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hisB, MT1637, MTCY336.03c, Rv1601 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Imidazoleglycerol-phosphate_dehydratase Imidazoleglycerol-phosphate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.19 4.2.1.19] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gqu OCA], [http://pdbe.org/4gqu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gqu RCSB], [http://www.ebi.ac.uk/pdbsum/4gqu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gqu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HIS7_MYCTU HIS7_MYCTU]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Imidazoleglycerol-phosphate dehydratase]]
[[Category: Large Structures]]
[[Category: Ahangar, M S]]
[[Category: Biswal, B K]]
[[Category: Nasir, N]]
[[Category: Vyas, R]]
[[Category: Class- alpha and beta fold- ribosomal protein s5 domain 2-like super family-ribosomal protein s5 domain 2-like family- imidazole glycerol phoshate dehydratase domain- imidazole glycerol phosphate dehydratase]]
[[Category: Dehydratase]]
[[Category: Histidine biosynthesis]]
[[Category: Lyase]]
[[Category: Manganese]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Ahangar MS]]
[[Category: Biswal BK]]
[[Category: Nasir N]]
[[Category: Vyas R]]

Revision as of 07:11, 26 October 2022

Crystal structure of HisB from Mycobacterium tuberculosis

4gqu, resolution 2.02Å

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