4gsy: Difference between revisions
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==Crystal structure of thymidylate kinase from Staphylococcus aureus bound to inhibitor.== | ==Crystal structure of thymidylate kinase from Staphylococcus aureus bound to inhibitor.== | ||
<StructureSection load='4gsy' size='340' side='right' caption='[[4gsy]], [[Resolution|resolution]] 1.71Å' scene=''> | <StructureSection load='4gsy' size='340' side='right'caption='[[4gsy]], [[Resolution|resolution]] 1.71Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4gsy]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4gsy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GSY FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0Y5:4-{[(3S)-3-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)PIPERIDIN-1-YL]METHYL}-2-[3-(TRIFLUOROMETHYL)PHENOXY]BENZOIC+ACID'>0Y5</scene | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0Y5:4-{[(3S)-3-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)PIPERIDIN-1-YL]METHYL}-2-[3-(TRIFLUOROMETHYL)PHENOXY]BENZOIC+ACID'>0Y5</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gsy OCA], [https://pdbe.org/4gsy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gsy RCSB], [https://www.ebi.ac.uk/pdbsum/4gsy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gsy ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/KTHY_STAAR KTHY_STAAR] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Thymidylate kinase|Thymidylate kinase]] | *[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Staphylococcus aureus subsp. aureus N315]] | ||
[[Category: Larsen | [[Category: Larsen NA]] | ||
[[Category: Olivier | [[Category: Olivier NB]] | ||
Revision as of 07:15, 26 October 2022
Crystal structure of thymidylate kinase from Staphylococcus aureus bound to inhibitor.
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