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==Crystal Structure of the Response Regulator Protein VraR from Staphylococcus aureus==
==Crystal Structure of the Response Regulator Protein VraR from Staphylococcus aureus==
<StructureSection load='4gvp' size='340' side='right' caption='[[4gvp]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
<StructureSection load='4gvp' size='340' side='right'caption='[[4gvp]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4gvp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staam Staam]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GVP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GVP FirstGlance]. <br>
<table><tr><td colspan='2'>[[4gvp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GVP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GVP FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SAV1884, vraR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 STAAM])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gvp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gvp OCA], [https://pdbe.org/4gvp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gvp RCSB], [https://www.ebi.ac.uk/pdbsum/4gvp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gvp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gvp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gvp OCA], [http://pdbe.org/4gvp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gvp RCSB], [http://www.ebi.ac.uk/pdbsum/4gvp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gvp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/VRAR_STAAM VRAR_STAAM]] Member of the two-component regulatory system VraS/VraR involved in the control of the cell wall peptidoglycan biosynthesis. VraR is overexpressed in strain Mu50, which leads to vancomycin resistance.  
[https://www.uniprot.org/uniprot/VRAR_STAAM VRAR_STAAM] Member of the two-component regulatory system VraS/VraR involved in the control of the cell wall peptidoglycan biosynthesis. VraR is overexpressed in strain Mu50, which leads to vancomycin resistance.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Response regulator|Response regulator]]
*[[Response regulator 3D structure|Response regulator 3D structure]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Staam]]
[[Category: Large Structures]]
[[Category: Leonard, P G]]
[[Category: Staphylococcus aureus subsp. aureus Mu50]]
[[Category: Stock, A M]]
[[Category: Leonard PG]]
[[Category: Bacterial signalling]]
[[Category: Stock AM]]
[[Category: Dna binding]]
[[Category: Response regulator]]
[[Category: Transcription]]
[[Category: Transcription factor]]
[[Category: Two-component system]]
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